Implantable Neural Interfaces and Wearable Tactile Systems for Bidirectional Neuroprosthetics Systems.,Advanced Healthcare Materials

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Implantable Neural Interfaces and Wearable Tactile Systems for Bidirectional Neuroprosthetics Systems.
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2019-11-25 , DOI: 10.1002/adhm.201801345
Annarita Cutrone ₁ , Silvestro Micera _{1,

2}

Affiliation

Neuroprosthetics and neuromodulation represent a promising field for several related applications in the central and peripheral nervous system, such as the treatment of neurological disorders, the control of external robotic devices, and the restoration of lost tactile functions. These actions are allowed by the neural interface, a miniaturized implantable device that most commonly exploits electrical energy to fulfill these operations. A neural interface must be biocompatible, stable over time, low invasive, and highly selective; the challenge is to develop a safe, compact, and reliable tool for clinical applications. In case of anatomical impairments, neuroprosthetics is bound to the need of exploring the surrounding environment by fast-responsive and highly sensitive artificial tactile sensors that mimic the natural sense of touch. Tactile sensors and neural interfaces are closely interconnected since the readouts from the first are required to convey information to the neural implantable apparatus. The role of these devices is pivotal hence technical improvements are essential to ensure a secure system to be eventually adopted in daily life. This review highlights the fundamental criteria for the design and microfabrication of neural interfaces and artificial tactile sensors, their use in clinical applications, and future enhancements for the release of a second generation of devices.

中文翻译：

双向神经修复系统的可植入神经接口和可穿戴触觉系统。

神经修复和神经调节代表了中枢和周围神经系统中若干相关应用的有前途的领域，例如神经系统疾病的治疗，外部机器人设备的控制以及失去的触觉功能的恢复。神经接口允许这些动作，神经接口是一种微型植入式设备，通常会利用电能来完成这些操作。神经接口必须具有生物相容性，长期稳定，低侵入性和高度选择性。面临的挑战是为临床应用开发安全，紧凑和可靠的工具。在解剖结构受损的情况下，神经假肢必须通过模仿自然触摸感的快速响应和高度灵敏的人工触觉传感器来探索周围环境。触觉传感器和神经接口紧密相连，因为需要从第一个读出以将信息传递到神经可植入设备。这些设备的作用至关重要，因此，技术改进对于确保安全系统最终应用于日常生活至关重要。这篇综述重点介绍了神经接口和人工触觉传感器的设计和微制造的基本标准，它们在临床应用中的使用以及未来发布第二代设备的增强功能。这些设备的作用至关重要，因此，技术改进对于确保安全系统最终应用于日常生活至关重要。这篇综述重点介绍了神经接口和人工触觉传感器的设计和微制造的基本标准，它们在临床应用中的使用以及未来发布第二代设备的增强功能。这些设备的作用至关重要，因此，技术改进对于确保安全系统最终应用于日常生活至关重要。这篇综述重点介绍了神经接口和人工触觉传感器的设计和微制造的基本标准，它们在临床应用中的使用以及未来发布第二代设备的增强功能。

更新日期：2019-12-19

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