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Oxidation of CLOCK boosts circadian rhythms.
Nature Cell Biology ( IF 21.3 ) Pub Date : 2019-12-01 , DOI: 10.1038/s41556-019-0430-2
Ueli Schibler 1
Affiliation  

In mammals, a circadian timing system composed of a master clock in the brain’s suprachiasmatic nucleus and oscillators in peripheral organs drives daily rhythms of behavior and physiology. A study now reveals that the periodic oxidation of the CLOCK protein enhances the amplitude of cyclic gene expression and affects the daily rhythms of behavior.

中文翻译:

CLOCK 的氧化可促进昼夜节律。

在哺乳动物中,由大脑视交叉上核中的主时钟和外围器官中的振荡器组成的昼夜节律系统驱动着日常行为和生理节律。现在的一项研究表明,CLOCK 蛋白的周期性氧化增强了循环基因表达的幅度并影响了日常行为节律。
更新日期:2019-11-26
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