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Nanoparticles-based magnetic and photo induced hyperthermia for cancer treatment
Nano Today ( IF 13.2 ) Pub Date : 2019-12-01 , DOI: 10.1016/j.nantod.2019.100795
S.K. Sharma , Navadeep Shrivastava , Francesco Rossi , Le Duc Tung , Nguyen Thi Kim Thanh

Abstract Nanoscience provides several modalities to combat cancer disease effectively. Magnetic hyperthermia and photothermal therapy techniques are central research themes among various groups in the world by utilizing magnetic and optical characteristics of distinct or composite nanoentities. This review provides the current research on both the techniques and their successes towards clinical translation. This review discusses about the various heating mechanisms involved in magnetic and photo-induced hyperthermia. We have evaluated potential functional nanoparticles with excellent properties capable of providing innovative future solutions to current problems associated with these therapies. Several factors (extracellular and intracellular) have been covered and explained which may affect such thermal treatments. We have provided some instrumental and technical details of both the techniques that are important for consideration in using these modalities of treatments. A direct comparison of these two techniques and a further need of the combined therapy (magnetic hyperthermia plus photothermal therapy) was highlighted as a new pathway for cancer treatments.

中文翻译:

基于纳米粒子的磁性和光致热疗用于癌症治疗

摘要 纳米科学提供了多种有效对抗癌症疾病的方法。利用不同或复合纳米实体的磁和光学特性,磁热疗和光热治疗技术是世界上各个群体的核心研究主题。这篇综述提供了目前对临床转化技术及其成功的研究。本综述讨论了磁性和光致热疗中涉及的各种加热机制。我们评估了具有优异特性的潜在功能性纳米粒子,能够为与这些疗法相关的当前问题提供创新的未来解决方案。已经涵盖并解释了可能影响此类热处理的几个因素(细胞外和细胞内)。我们提供了这两种技术的一些仪器和技术细节,这对于使用这些治疗方式很重要。这两种技术的直接比较以及对联合疗法(磁热疗加光热疗法)的进一步需求被强调为癌症治疗的新途径。
更新日期:2019-12-01
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