In addition to redefining essential tremor (ET), the 2018 consensus statement of the Movement Disorder Society on tremor coined a new term: essential tremor-plus (ET-plus). This term is uncertainly defined as tremor with the characteristics of ET, with additional neurological signs of uncertain clinical significance. If ET-plus had been defined on the basis of a difference in underlying pathology or an appreciable difference in prognosis, it would have a valid, scientific rationale, as does the term Parkinson-plus. However, there is no such evidence, so the basis for the term is questionable. In fact, ET-plus might only represent a state condition (ie, patients with ET might develop these additional clinical features when the disease is at a more advanced stage). We caution against coining new terms that are not supported by a firm scientific basis and encourage research into the creation of essential tremor subsets that are defined with respect to differences in underlying causes or pathophysiology.

中文翻译：

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特发性震颤加重：一个有争议的新概念

除了重新定义特发性震颤（ET）外，2018年运动障碍学会关于震颤的共识声明还创造了一个新术语：特发性震颤+（ET-plus）。该术语的定义不确定，即具有 ET 特征的震颤，并伴有临床意义不确定的其他神经系统体征。如果 ET-plus 是根据基础病理学的差异或预后的明显差异来定义的，那么它就会有一个有效的、科学的理由，就像帕金森+这个术语一样。然而，没有这样的证据，因此该术语的基础值得怀疑。事实上，ET-plus 可能仅代表一种状态（即，当疾病处于更晚期阶段时，ET 患者可能会出现这些额外的临床特征）。我们警告不要创造没有坚实科学基础支持的新术语，并鼓励研究创建根据根本原因或病理生理学差异定义的特发性震颤子集。