当前位置: X-MOL 学术Eur. Urol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Multiparametric Magnetic Resonance Imaging for the Detection of Clinically Significant Prostate Cancer: What Urologists Need to Know. Part 2: Interpretation
European Urology ( IF 25.3 ) Pub Date : 2019-11-23 , DOI: 10.1016/j.eururo.2019.10.024
Bas Israël , Marloes van der Leest , Michiel Sedelaar , Anwar R. Padhani , Patrik Zámecnik , Jelle O. Barentsz

Background

There is large variability among radiologists in their detection of clinically significant (cs) prostate cancer (PCa) on multiparametric magnetic resonance imaging (mpMRI).

Objective

To reduce the interpretation variability and achieve optimal accuracy in assessing prostate mpMRI.

Design, setting, and participants

How the interpretation of mpMRI can be optimized is demonstrated here. Whereas part 1 of the “surgery-in-motion” paper focused on acquisition, this paper shows the correlation between (ab)normal prostate anatomical structures and image characteristics on mpMRI, and how standardized interpretation according to Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) should be performed. This will be shown in individual patients.

Surgical procedure

To detect csPCa, three mpMRI “components” are used: “anatomic” T2-weighted imaging, “cellular-density” diffusion-weighted imaging, and “vascularity” dynamic contrast-enhanced MRI.

Measurements

Based on PI-RADS v2, the accompanying video shows how mpMRI interpretation is performed. Finally, the role of mpMRI in detecting csPCa is briefly discussed and the main features of the recently introduced PI-RADS v2.1 are evaluated.

Results and limitations

With PI-RADS v2, it is possible to quantify normal and abnormal anatomical structures within the prostate based on its imaging features of the three mpMRI “components.” With this knowledge, a more objective evaluation of the presence of a csPCa can be performed. However, there still remains quite some space to reduce interobserver variability.

Conclusions

For understanding the interpretation of mpMRI according to PI-RADS v2, knowledge of the correlation between imaging and (ab)normal anatomical structures on the three mpMRI components is needed.

Patient summary

This second surgery-in-motion contribution shows what structures can be recognized on prostate magnetic resonance imaging (MRI). How a radiologist performs his reading according to the so-called Prostate Imaging Reporting and Data System criteria is shown here. The main features of these criteria are summarized, and the role of prostate MRI in detecting clinically significant prostate cancer is discussed briefly.



中文翻译:

多参数磁共振成像技术用于检测临床上重要的前列腺癌:泌尿科医师需要知道的。第2部分:释义

背景

放射科医生在多参数磁共振成像(mpMRI)上对临床上显着(cs)前列腺癌(PCa)的检测中存在很大差异。

客观的

为了减少解释变异性并在评估前列腺mpMRI时达到最佳准确性。

设计,设置和参与者

此处演示了如何优化mpMRI的解释。“运动外科”论文的第1部分着重于采集,而本文则显示了(异常)正常前列腺解剖结构与mpMRI上的图像特征之间的相关性,以及如何根据前列腺成像报告和数据系统第2版进行标准化解释(PI-RADS v2)应该被执行。这将在个别患者中显示。

手术程序

为了检测csPCa,使用了三个mpMRI“组件”:“解剖” T2加权成像,“细胞密度”扩散加权成像和“血管”动态对比增强MRI。

测量

随附的视频基于PI-RADS v2,显示了如何执行mpMRI解释。最后,简要讨论了mpMRI在检测csPCa中的作用,并评估了最近推出的PI-RADS v2.1的主要功能。

结果与局限性

借助PI-RADS v2,可以根据其对mpmp三个“成分”的成像特征来量化前列腺内正常和异常的解剖结构。有了这些知识,就可以对csPCa的存在进行更客观的评估。但是,仍然存在相当大的空间来减少观察者之间的差异。

结论

为了理解根据PI-RADS v2对mpMRI的解释,需要了解三个mpMRI组件上的成像与正常解剖结构之间的相关性。

病人总结

这第二项运动中的手术贡献显示了可以在前列腺磁共振成像(MRI)上识别出哪些结构。此处显示了放射科医生如何根据所谓的“前列腺影像报告和数据系统”标准执行其阅读。总结了这些标准的主要特征,并简要讨论了前列腺MRI在检测具有临床意义的前列腺癌中的作用。

更新日期:2019-11-26
down
wechat
bug