Biological receptors distinguish between S- and R-enantiomers and these subtle differences in chirality can lead to vastly different protein affinities. Now, a proteomics approach has been developed that capitalizes on chirality to map enantiomeric probe pairs and provides a rapid and global view of protein ligandability within the cell.

中文翻译：

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绘制蛋白质配体性的手性技巧

生物受体区分S和R对映异构体，并且手性的这些细微差别可以导致蛋白质亲和力大大不同。现在，已开发出一种蛋白质组学方法，该方法可利用手性来绘制对映体探针对，并提供细胞内蛋白质配体能力的快速全局视图。