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Early‐stage Parkinson's patients show selective impairment in reactive but not proactive inhibition
Movement Disorders ( IF 7.4 ) Pub Date : 2019-11-21 , DOI: 10.1002/mds.27920 Veronica Di Caprio 1 , Nicola Modugno 1 , Christian Mancini 2 , Enrica Olivola 1 , Giovanni Mirabella 1, 2
Movement Disorders ( IF 7.4 ) Pub Date : 2019-11-21 , DOI: 10.1002/mds.27920 Veronica Di Caprio 1 , Nicola Modugno 1 , Christian Mancini 2 , Enrica Olivola 1 , Giovanni Mirabella 1, 2
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It is well known that a deficit in inhibitory control is a hallmark of Parkinson's disease (PD). However, inhibition is not a unitary construct, and it is unclear whether patients in the early stage of the disease (Hoehn and Yahr stage 1) exhibit a deficit in outright stopping (reactive inhibition), a deficit in the ability to shape their response strategies according to the context (proactive inhibition), or both.
中文翻译:
早期帕金森病患者在反应性而非主动性抑制方面表现出选择性损害
众所周知,抑制控制的缺陷是帕金森病 (PD) 的标志。然而,抑制并不是一个单一的结构,目前尚不清楚处于疾病早期阶段(Hoehn 和 Yahr 1 期)的患者是否表现出完全停止(反应性抑制)的缺陷,即形成其反应策略的能力缺陷根据上下文(主动抑制),或两者兼而有之。
更新日期:2019-11-21
中文翻译:
早期帕金森病患者在反应性而非主动性抑制方面表现出选择性损害
众所周知,抑制控制的缺陷是帕金森病 (PD) 的标志。然而,抑制并不是一个单一的结构,目前尚不清楚处于疾病早期阶段(Hoehn 和 Yahr 1 期)的患者是否表现出完全停止(反应性抑制)的缺陷,即形成其反应策略的能力缺陷根据上下文(主动抑制),或两者兼而有之。