In The Lancet Psychiatry, Morgan Philbin and Pia Mauro report an increase in the use of non-prescription drugs since 2000. Since 2010, this problem has largely affected patients who simultaneously take new psychoactive substances and other drugs. As a result, polypharmacotherapy is included in the treatment. This factor increases the risk of re-admission of the same patients to hospital and the resulting costs of treatment—eg, in schizophrenia. Incorrect drug administration, known as polypragmasia, can cause severe therapeutic complications. We would like to draw attention to various types of web-based applications (eg, Medscape, Micromedex, Epocrates) that enable clinicians to search for information on the mutual effect of substances when administered simultaneously, and that are, unfortunately, largely neglected by psychiatrists globally.

中文翻译：

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药物相互作用的药理基础：精神病学中一个被忽视的方面。

在柳叶刀精神病学中，Morgan Philbin和Pia Mauro报告说，自2000年以来，非处方药的使用有所增加。自2010年以来，这一问题在很大程度上影响了同时服用新的精神活性物质和其他药物的患者。结果，多药物疗法被包括在治疗中。该因素增加了同一患者再次入院的风险以及由此产生的治疗费用，例如精神分裂症。药物管理不当（称为多发性汗腺症）会导致严重的治疗并发症。我们想提请注意基于网络的各种类型的应用程序（例如Medscape，Micromedex，Epocrates），这些应用程序使临床医生可以在同时给药时搜索有关物质相互作用的信息，但不幸的是，精神病医生很大程度上忽略了这些信息全球范围。