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Enzyme Allostery: Now Controllable by Light.
Cell Chemical Biology ( IF 6.6 ) Pub Date : 2019-11-21 , DOI: 10.1016/j.chembiol.2019.11.001
Taylor M Courtney 1 , Alexander Deiters 1
Affiliation  

In this issue of Cell Chemical Biology, the Sterner lab reports the application of photoswitchable unnatural amino acids in controlling protein allostery in the enzyme complex imidazole glycerol phosphate synthase (Kneuttinger et al., 2019). Remarkable switching in enzyme activity was achieved upon photoisomerization of an azobenzene amino acid.

中文翻译:

酶变构:现在可以通过光控制。

在本期《细胞化学生物学》中,Sterner实验室报告了光可转换非天然氨基酸在控制酶复合物咪唑甘油磷酸合酶中的蛋白质变构中的应用(Kneuttinger等人,2019)。通过偶氮苯氨基酸的光异构化实现酶活性的显着改变。
更新日期:2019-11-22
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