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Dawn of a New Era of Targeted Antioxidant Therapies.
Cell Chemical Biology ( IF 6.6 ) Pub Date : 2019-11-21 , DOI: 10.1016/j.chembiol.2019.11.003
Brent R Stockwell 1
Affiliation  

In this issue of Cell Chemical Biology, Shah et al. (2019) report an in vitro, high-throughput assay that predicts the ability of compounds to suppress peroxidation of phospholipids. This approach provides a way to design and optimize targeted antioxidants that suppress specific oxidative event in cells, potentially overcoming previous failures with generic antioxidants.

中文翻译:

靶向抗氧化疗法新时代的来临。

在本期《细胞化学生物学》中,Shah等人。(2019)报告了一种体外高通量测定方法,该方法可预测化合物抑制磷脂过氧化的能力。这种方法提供了一种设计和优化靶向抗氧化剂的方法,该抗氧化剂可抑制细胞中的特定氧化事件,从而有可能克服以前使用普通抗氧化剂的失败。
更新日期:2019-11-22
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