To the Editor We read with great interest the work by Theelen et al,¹ which reported that treatment with pembrolizumab combined with radiotherapy had a manageable safety profile and synergistic effect. We think that the work provides powerful clinical data to this field. Although the authors suggested that radiotherapy prior to treatment with pembrolizumab was well tolerated and conferred notably improved outcomes, we would like to raise 3 points for discussion.

中文翻译：

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超越 PEMBRO-RT 试验的结果

致编辑我们非常感兴趣地阅读了 Theelen 等人¹的工作，该工作报告说，派姆单抗联合放射治疗具有可控的安全性和协同效应。我们认为这项工作为该领域提供了强大的临床数据。尽管作者建议在使用派姆单抗治疗之前进行放射治疗具有良好的耐受性并显着改善了结果，但我们想提出 3 点讨论。