Preferential interactions of α-chymotrypsinogen in water and aqueous solutions of ethylene glycol, glycerol, erythritol, sorbitol, and inositol were studied from precise density measurements under conditions of constant molality and constant chemical potential; to achieve the last condition, solutions were brought under equilibrium dialysis. The density measurements were performed at 298.15 K and they were used to determine the preferential interaction parameters. The results confirm a significant correlation between the numbers of hydroxyl groups of the polyols with the stability of α-chymotrypsinogen.

中文翻译：

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298.15 K 下多元醇水溶液中糜蛋白酶原的优先相互作用

在恒定摩尔浓度和恒定化学势条件下，通过精确的密度测量研究了 α-胰凝乳蛋白酶原在乙二醇、甘油、赤藓糖醇、山梨糖醇和肌醇的水溶液中的优先相互作用；为达到最后一个条件，使溶液处于平衡透析状态。密度测量在 298.15 K 下进行，它们用于确定优先相互作用参数。结果证实了多元醇的羟基数量与α-胰凝乳蛋白酶原稳定性之间的显着相关性。