Artificial micromotors have a demonstrated value in biomedical area. Attempts to develop this technology tend to impart micromotors novel functions to improve the values. Herein, we present novel structural color barcode micromotors for the multiplex assays. We found that by rapid extracting solvent and assembling monodispersed nanoparticles in droplets, it could form stomatocyte colloidal crystal clusters, which not only showed striking structural colors and characteristic reflection peaks due to their ordered nanoparticles arrangement, but also provided effective cavities for the integration of functional elements. Thus, the micromotors with catalyst or magnetic elements in their cavities, as well as with corresponding structural color coding, could be achieved by using the platinum and ferric oxide dispersed pre-gel to fill and duplicate the stomatocyte colloidal crystal clusters. We have demonstrated that the self-movement of these structural color barcode micromotors could efficiently accelerate the mixing speed of the detection sample and greatly increase the probe-target interactions towards faster and more sensitive single or multiplex detection, and the magnetism of these barcode micromotors enables the flexible collection of the micromotors, which could facilitate the detection processes. These features make the stomatocyte structural color barcode micromotors ideal for biomedical applications.

中文翻译：

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用于多重检测的口腔细胞结构颜色条形码微电机

人工微电机在生物医学领域具有示范价值。尝试开发这项技术往往会赋予微电机新的功能以提高价值。在此，我们提出了用于多重检测的新型结构颜色条形码微电机。我们发现通过快速提取溶剂和将单分散的纳米颗粒组装在液滴中，可以形成口腔细胞胶体晶体簇，由于纳米颗粒的有序排列，不仅显示出醒目的结构颜色和特征反射峰，而且为功能的整合提供了有效的空腔。元素。因此，微电机在其腔体中带有催化剂或磁性元件，以及相应的结构颜色编码，可以通过使用铂和氧化铁分散的预凝胶填充和复制口腔细胞胶体晶体簇来实现。我们已经证明，这些结构色条码微电机的自运动可以有效地加快检测样品的混合速度，并大大增加探针-目标相互作用，实现更快、更灵敏的单一或多重检测，并且这些条码微电机的磁性使微电机的灵活集​​合，可以促进检测过程。这些特点使口腔细胞结构颜色条码微电机成为生物医学应用的理想选择。我们已经证明，这些结构色条码微电机的自运动可以有效地加快检测样品的混合速度，并大大增加探针-目标相互作用，实现更快、更灵敏的单一或多重检测，并且这些条码微电机的磁性使微电机的灵活集​​合，可以促进检测过程。这些特点使口腔细胞结构颜色条码微电机成为生物医学应用的理想选择。我们已经证明，这些结构色条码微电机的自运动可以有效地加快检测样品的混合速度，并大大增加探针-目标相互作用，实现更快、更灵敏的单一或多重检测，并且这些条码微电机的磁性使微电机的灵活集​​合，可以促进检测过程。这些特点使口腔细胞结构颜色条码微电机成为生物医学应用的理想选择。