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Clinical meaningfulness of subtle cognitive decline on longitudinal testing in preclinical AD
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2020-01-04 , DOI: 10.1016/j.jalz.2019.09.074 Kathryn V Papp 1, 2 , Rachel Buckley 2 , Elizabeth Mormino 3 , Paul Maruff 4, 5 , Victor L Villemagne 6 , Colin L Masters 4 , Keith A Johnson 1, 2, 7 , Dorene M Rentz 1, 2 , Reisa A Sperling 1, 2 , Rebecca E Amariglio 1, 2 ,
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2020-01-04 , DOI: 10.1016/j.jalz.2019.09.074 Kathryn V Papp 1, 2 , Rachel Buckley 2 , Elizabeth Mormino 3 , Paul Maruff 4, 5 , Victor L Villemagne 6 , Colin L Masters 4 , Keith A Johnson 1, 2, 7 , Dorene M Rentz 1, 2 , Reisa A Sperling 1, 2 , Rebecca E Amariglio 1, 2 ,
Affiliation
Demonstrating the “clinical meaningfulness” of slowing early cognitive decline in clinically normal (CN) older adults with elevated amyloid‐β (Aβ+) is critical for Alzheimer's disease secondary prevention trials and for understanding early cognitive progression.
中文翻译：
临床前 AD 纵向测试中轻微认知能力下降的临床意义
证明淀粉样蛋白-β (Aβ+) 升高的临床正常 (CN) 老年人减缓早期认知衰退的“临床意义”对于阿尔茨海默病二级预防试验和了解早期认知进展至关重要。
更新日期：2020-01-04
中文翻译：
临床前 AD 纵向测试中轻微认知能力下降的临床意义
证明淀粉样蛋白-β (Aβ+) 升高的临床正常 (CN) 老年人减缓早期认知衰退的“临床意义”对于阿尔茨海默病二级预防试验和了解早期认知进展至关重要。
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