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Docking Complete: A Step Further toward the Holy Grail of γδ T Cell Biology.
Immunity ( IF 25.5 ) Pub Date : 2019-11-19 , DOI: 10.1016/j.immuni.2019.10.013
Ningning Cai 1 , Shuai Han 1 , Yonghui Zhang 1
Affiliation  

The direct ligands recognized by γδ T cell receptors (γδ TCRs) remain uncertain and controversial. In a study appearing in this issue, Willcox et al. use surface plasmon resonance and isothermal titration calorimetry to demonstrate that B7-like molecule BTNL3 makes physical contact with V4γ-bearing TCRs on γδ T cells.

中文翻译:

对接完成:进一步迈向γδT细胞生物学的圣杯。

γδT细胞受体(γδTCR)识别的直接配体仍然不确定和有争议。在此期出现的一项研究中,Willcox等人。使用表面等离振子共振和等温滴定热法来证明B7样分子BTNL3与γδT细胞上带有V4γ的TCR物理接触。
更新日期:2019-11-20
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