3D Helical Micromixer Fabricated by Micro Lost‐Wax Casting,Advanced Materials Technologies

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3D Helical Micromixer Fabricated by Micro Lost‐Wax Casting
Advanced Materials Technologies ( IF 6.4 ) Pub Date : 2019-11-20 , DOI: 10.1002/admt.201900794
Daiki Tachibana ₁ , Ken Matsubara ₁ , Ryosuke Matsuda ₁ , Taichi Furukawa _{1,

2} , Shoji Maruo _{1,

2} , Yoshimi Tanaka ₃ , Ohmi Fuchiwaki _{1,

2} , Hiroki Ota _{1,

2}

Affiliation

Micromixers produced by micro fabrication techniques have attracted attention for micro total analysis systems and lab‐on‐a‐chip applications in point‐of‐care testing. However, the fabrication and setup of micromixers have become more complex and more difficult. Considering the practical use of micromixers in medical and industrial applications, their designs can be simplified while maintaining high mixing efficiency. Rapid prototyping, represented by 3D printing having micro‐scale resolutions, is one promising technology to replace conventional fabrication methods such as soft lithography. Here, a 3D helical micromixer fabricated by micro‐scale lost‐wax casting is reported. The molds for lost‐wax casting are fabricated by fine 3D printing of a hard wax resin which can be removed from a polydimethylsiloxane block just by heating and washing with water, and a fine and smooth structure is realized. The optimized helical micromixer fabricated by lost‐wax casting promotes mixing efficiency compared with other micromixers. In addition, a monolithic microchannel having the helical 3D bridge structure is presented in this study. The demonstration is an important advancement toward the industrial applications of micromixers fabricated by micro‐scale 3D printing. The ability to fabricate complex structures can simply lead to the creation of more sophisticated mixers in the future.

中文翻译：

通过微失蜡铸造制造的3D螺旋微混合器

通过微型制造技术生产的微型混合器已在微型整体分析系统和即时检验中的芯片实验室应用中引起了关注。然而，微型混合器的制造和设置变得更加复杂和困难。考虑到微型混合器在医疗和工业应用中的实际使用，可以在保持高混合效率的同时简化其设计。以具有微型分辨率的3D打印为代表的快速成型技术，是一种有前途的技术，可以代替传统的制造方法（例如软光刻）。在这里，报道了一种通过微缩蜡铸造制造的3D螺旋微混合器。失蜡铸造用的模具是通过对硬质蜡树脂进行精细的3D打印而制成的，只需加热和用水清洗就可以将其从聚二甲基硅氧烷嵌段中去除，从而实现了精细而光滑的结构。与其他微混合器相比，通过失蜡铸造制造的优化螺旋微混合器可提高混合效率。此外，本研究还介绍了具有螺旋3D桥结构的单片微通道。该演示是通过微型3D打印制造的微型混合器在工业应用方面的重要进步。制造复杂结构的能力可以简单地导致将来创建更复杂的混合器。与其他微混合器相比，通过失蜡铸造制造的优化螺旋微混合器可提高混合效率。此外，本研究还介绍了具有螺旋3D桥结构的单片微通道。该演示是通过微型3D打印制造的微型混合器在工业应用方面的重要进步。制造复杂结构的能力可以简单地导致将来创建更复杂的混合器。与其他微混合器相比，通过失蜡铸造制造的优化螺旋微混合器可提高混合效率。此外，本研究还介绍了具有螺旋3D桥结构的单片微通道。该演示是通过微型3D打印制造的微型混合器在工业应用方面的重要进步。制造复杂结构的能力可以简单地导致将来创建更复杂的混合器。

更新日期：2020-01-13

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