Cytokines have context-dependent roles that dictate their normal physiological function; however, dysregulation or chronic activation of cytokine pathways can alter tissue balance away from a return to homeostatic quiescence toward disease-associated immunopathology.

中文翻译：

---

细胞因子处于平衡状态。

细胞因子具有取决于情境的作用，决定着它们的正常生理功能。然而，细胞因子途径的失调或慢性激活可以改变组织平衡，从而使平衡从静止状态的静止过渡到与疾病相关的免疫病理学。