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Time-series analysis of ambient PM2.5 and cardiorespiratory emergency room visits in Lima, Peru during 2010-2016.
Journal of Exposure Science and Environmental Epidemiology ( IF 4.1 ) Pub Date : 2019-11-19 , DOI: 10.1038/s41370-019-0189-3
V Tapia 1 , K Steenland 2 , S E Sarnat 2 , B Vu 2 , Y Liu 2 , O Sánchez-Ccoyllo 1, 3 , V Vasquez 1 , G F Gonzales 1
Affiliation  

INTRODUCTION There have been no time-series studies of air pollution in Peru. Here we evaluate the effect of ambient PM2.5 on emergency room (ER) visits in Lima. METHODS We estimated daily PM2.5 levels at a 1 km2 resolution during 2010-2016 using ground measurements, satellite data, and chemical transport model simulations. Population-weighted average daily PM2.5 levels were calculated for each district in Lima (n = 40), and assigned to patients based on residence. ER visits for respiratory and circulatory diseases were gathered from nine large public hospitals. Poisson regression was used to estimate the rate ratio for daily ER visits with change in daily PM2.5, controlling for meteorology, time trends, and district. RESULTS For each interquartile range (IQR) increase in PM2.5, respiratory disease ER visits increased 4% (95% CI: 0-5%), stroke visits 10% (3-18%), and ischemic heart disease visits (adults, 18-64 years) 11% (-1, 24%). Districts with higher poverty showed significantly stronger associations of PM2.5 and respiratory disease ER visits than districts with lower poverty. Effects were diminished 24-42% using Lima-wide instead of district-specific PM2.5 levels. CONCLUSIONS Short-term exposure to ambient PM2.5 is associated with increases in ER visits in Lima for respiratory diseases and stroke, and among middle-aged adults, ischemic heart disease.

中文翻译:

2010-2016 年秘鲁利马环境 PM2.5 和心肺急诊就诊的时间序列分析。

引言 秘鲁没有关于空气污染的时间序列研究。在这里,我们评估了环境 PM2.5 对利马急诊室 (ER) 就诊的影响。方法 我们使用地面测量、卫星数据和化学传输模型模拟估计了 2010-2016 年 1 km2 分辨率的每日 PM2.5 水平。计算了利马每个地区(n = 40)的人口加权平均每日 PM2.5 水平,并根据居住地分配给患者。从九家大型公立医院收集了呼吸道和循环系统疾病的急诊就​​诊。泊松回归用于估计每日急诊室就诊率与每日 PM2.5 变化的比率,控制气象、时间趋势和地区。结果 PM2.5 每增加一个四分位距 (IQR),呼吸系统疾病急诊就诊增加 4%(95% CI:0-5%),卒中就诊 10% (3-18%),缺血性心脏病就诊(成人,18-64 岁)11% (-1, 24%)。与贫困程度较低的地区相比,贫困程度较高的地区与 PM2.5 和呼吸道疾病急诊就诊的相关性明显更强。使用利马范围而不是特定地区的 PM2.5 水平,影响减少了 24-42%。结论 短期暴露于环境 PM2.5 与利马因呼吸系统疾病和中风以及中年人缺血性心脏病的急诊就​​诊增加有关。
更新日期:2019-11-19
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