Transposons and other repetitive sequences make up a large part of complex genomes. Repetitive sequences can be co-opted into a variety of functions and thus provide a source for evolutionary novelty. However, comprehensively detecting ancestral repeats that align between species is difficult because considering all repeat-overlapping seeds in alignment methods that rely on the seed-and-extend heuristic results in prohibitively high runtimes.

中文翻译：

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RepeatFiller 新识别了比对重复序列的兆碱基并改进了保守非外显子元素的注释

转座子和其他重复序列构成了复杂基因组的很大一部分。重复序列可以被增选为多种功能，从而为进化新颖性提供来源。然而，全面检测物种之间对齐的祖先重复是很困难的，因为在依赖于种子和扩展启发式结果的对齐方法中考虑所有重复重叠的种子，运行时间非常高。