In the continuous search for the improvement of processes, recently, alternative schemes have been proposed to separate and purify levulinic acid produced from the acid hydrolysis of biomass. These alternatives offer both energy and economic savings, and reduction of environmental impact; however, their control properties have not been considered for possible industrial implementation. In this work, a controllability analysis was carried out of previously optimized designs using the relative gain array (RGA), the total condition number (TCN) and a sensitivity index for performance assessment in open-loop. Finally, the dynamic performance in closed-loop is evaluated using PI controllers having as criteria the integral absolute error (IAE). Through analysis, the best scheme obtained presented a low total condition number, however, its sensitivity index is below the average of all the designs analyzed. Additionally, the RGA analysis shows a stable structure in the frequencies studied keeping low values of eco-indicators 99 and total annual cost. The general topology consists of a liquid-liquid extraction column, a conventional distillation column and a dividing wall column with a decanter. On the other hand, by means of this robust analysis of the control properties was proposed some guidelines between the structure for improving control properties in intensified distillation schemes.

在不断寻求改进方法的过程中，最近，已经提出了替代方案来分离和纯化由生物质的酸水解产生的乙酰丙酸。这些替代方案既节省了能源和经济，又减少了对环境的影响；但是，尚未考虑将其控制特性用于可能的工业实施。在这项工作中，使用相对增益阵列（RGA），总条件数（TCN）和用于开环性能评估的灵敏度指标，对先前优化的设计进行了可控性分析。最后，使用具有积分绝对误差（IAE）作为标准的PI控制器评估闭环的动态性能。通过分析，获得的最佳方案的总条件数较低，但是，其灵敏度指数低于所有分析设计的平均值。此外，RGA分析显示，在所研究的频率中具有稳定的结构，从而使生态指标的值保持在较低的水平99，并降低了年度总成本。通用拓扑由液-液萃取塔，常规蒸馏塔和带有with析器的分隔壁塔组成。另一方面，通过对控制特性的鲁棒性分析，提出了在强化蒸馏方案中用于改善控制特性的结构之间的一些指导原则。常规的蒸馏塔和带有倾析器的分隔壁塔。另一方面，通过对控制特性的这种鲁棒性分析，提出了在强化蒸馏方案中用于改善控制特性的结构之间的一些指导原则。常规的蒸馏塔和带有倾析器的分隔壁塔。另一方面，通过对控制特性的鲁棒性分析，提出了在强化蒸馏方案中用于改善控制特性的结构之间的一些指导原则。