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The mitochondrial gate reveals its secrets.
Nature Structural & Molecular Biology ( IF 12.5 ) Pub Date : 2019-12-01 , DOI: 10.1038/s41594-019-0346-3
Doron Rapaport 1
Affiliation  

Finally, the architecture of the translocase of the mitochondrial outer membrane (TOM complex) is revealed, after 20 years of anticipation. Two groups have now determined the near-atomic structures of the TOM complex. These findings improve understanding of the mechanisms by which TOM facilitates the passage of about 1,000 different proteins from the cytosol into the mitochondria.

中文翻译:

线粒体门揭示了它的秘密。

最后,经过 20 年的期待,线粒体外膜转位酶(TOM 复合体)的结构得以揭示。两个小组现在已经确定了 TOM 复合体的近原子结构。这些发现提高了对 TOM 促进大约 1,000 种不同蛋白质从胞质溶胶进入线粒体的机制的理解。
更新日期:2019-11-18
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