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Helminths Turning on the NLRP3 Inflammasome: Pros and Cons.
Trends in Parasitology ( IF 7.0 ) Pub Date : 2019-11-18 , DOI: 10.1016/j.pt.2019.10.012
Daiana Pamela Celias 1 , Claudia Cristina Motrán 1 , Laura Cervi 1
Affiliation  

Helminth infections can activate multimeric protein complexes called inflammasomes. In this forum we summarize the main effects of the NLRP3 inflammasome activation, including control of excessive Th2 response and immunopathology induction. These mechanisms would ensure the survival of both the host and the parasite.

中文翻译:

蠕虫打开NLRP3炎症小体的利弊。

蠕虫感染可以激活称为炎症小体的多聚体蛋白复合物。在本论坛中,我们总结了NLRP3炎性体激活的主要作用,包括控制过度的Th2反应和免疫病理学诱导。这些机制将确保宿主和寄生虫的生存。
更新日期:2019-11-18
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