INTRODUCTION Treatment of PD focuses on improving symptoms and quality of life, yet research has not examined interventions aimed at promoting hope in patients. This study examined the effects of a Strength, Hope, and Resources Program for People with PD (SHARP-PWP), based on the principles of positive psychology. METHODS A mixed method design examined the effects of a randomized, waitlist-controlled trial of SHARP-PWP. 31 PD patients diagnosed in the last 5 years (average age = 66; 13 men, 18 women) participated in a 6-session program. All participants completed self-report measures at pre-treatment, post-treatment, and 6-week follow-up. Data were analyzed using ANOVA. After the program, 15 participants completed a semi-structured interview. Qualitative interview data were analyzed using Interpretive Description. RESULTS No significant differences in improvement were found between the Immediate and Delayed intervention groups. However, significant effects for time (i.e., pre-treatment to post-treatment) were found for health-related quality of life and well-being in both Immediate and Delayed conditions. Additional quantitative analysis revealed significant improvement in both groups on hope from pre-treatment to follow-up. Qualitative findings revealed that clients identified social, emotional, behavioral and cognitive changes experienced in the group. CONCLUSIONS Participating in positive psychology research improved health-related quality of life (HrQoL) and mental health and patients identified additional benefits at 6-week follow-up. Our results provide insight about the placebo effect and Hawthorne pre-placebo effects in the context of PD research. The findings can inform trial design and clinical care of patients with PD.

中文翻译：

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力量，希望和机智计划对帕金森氏病（SHARP-PWP）的功效：一项混合方法研究。

引言PD的治疗着重于改善症状和生活质量，但研究尚未检查旨在促进患者希望的干预措施。这项研究基于积极心理学的原理，研究了针对PD患者的力量，希望和资源计划（SHARP-PWP）的效果。方法混合方法设计检查了SHARP-PWP的随机，候补对照试验的效果。最近5年中诊断出的31名PD患者（平均年龄= 66； 13名男性，18名女性）参加了为期6个疗程的计划。所有参与者在治疗前，治疗后和6周的随访中均完成了自我报告措施。使用ANOVA分析数据。计划结束后，有15名参与者完成了半结构化访谈。定性访谈数据使用解释性说明进行了分析。结果立即干预组和延迟干预组之间在改善方面没有发现显着差异。但是，对于即刻和延迟条件下与健康相关的生活质量和福祉，发现时间的显着影响（即从治疗前到治疗后）。进一步的定量分析显示，从治疗前到随访的​​希望，两组均显着改善。定性研究结果表明，客户发现了小组中经历的社交，情感，行为和认知方面的变化。结论参与积极的心理学研究可改善与健康相关的生活质量（HrQoL）和心理健康，并且患者在6周的随访中发现了其他益处。我们的结果在PD研究的背景下提供了关于安慰剂作用和霍桑安慰剂前作用的见解。