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Factors Associated With Measles Transmission in the United States During the Postelimination Era
JAMA Pediatrics ( IF 26.1 ) Pub Date : 2020-01-01 , DOI: 10.1001/jamapediatrics.2019.4357
Paul A Gastañaduy 1 , Sebastian Funk 2 , Benjamin A Lopman 3 , Paul A Rota 1 , Manoj Gambhir 4, 5 , Bryan Grenfell 6 , Prabasaj Paul 7
Affiliation  

Key Points Question What are the factors causing the transmission of measles in long-standing measles control programs? Findings This cross-sectional study found that lack of vaccination and birth on or after 1957, as well assortative transmission by age (particularly among school-aged children), are the primary factors associated with measles transmission in the United States. Although current measles vaccines are known to be highly effective in decreasing susceptibility to measles, these analyses shed light on the degree by which vaccination also limits measles transmission. Meaning The findings underscore the importance of maintaining homogenous, high, 2-dose measles vaccine coverage, especially among school-aged children, to sustain elimination of measles in the United States.

中文翻译:

消灭后时代与美国麻疹传播相关的因素

关键点 问题 在长期的麻疹控制计划中,导致麻疹传播的因素是什么?结果 这项横断面研究发现,在 1957 年或之后缺乏疫苗接种和出生,以及按年龄(尤其是学龄儿童)的分类传播,是与美国麻疹传播相关的主要因素。尽管已知目前的麻疹疫苗在降低麻疹易感性方面非常有效,但这些分析揭示了疫苗接种也限制麻疹传播的程度。意义 研究结果强调了保持均匀、高、2 剂麻疹疫苗覆盖率的重要性,尤其是在学龄儿童中,以维持在美国消除麻疹。
更新日期:2020-01-01
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