当前位置: X-MOL 学术Environ. Toxicol. Pharmacol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Nanoecotoxicology study of the response of magnetic O-Carboxymethylchitosan loaded silver nanoparticles on Artemia salina.
Environmental Toxicology and Pharmacology ( IF 4.2 ) Pub Date : 2019-11-16 , DOI: 10.1016/j.etap.2019.103298
Carla Albertina Demarchi 1 , Luisa Mota da Silva 1 , Anna Niedźwiecka 2 , Anna Ślawska-Waniewska 2 , Sabina Lewińska 2 , Jacir Dal Magro 3 , Jean Felipe Fossá Calisto 3 , Rafael Martello 3 , Clovis Antonio Rodrigues 1
Affiliation  

Magnetic silver nanoparticles (MNPAg) are interesting nanotechnology materials with borderless environmental science, that can be used to disinfect water contaminated with pathogenic bacteria. The use of MNPAg leads to increased risk of nanomaterial contamination in the environment, especially natural water sources, with harmful effects on the ecosystem. This study investigating survival and enzyme activity of magnetic O-carboxymethylchitosan loaded silver nanoparticle on Artemia salina. The results showed that mortality increased with increasing concentrations of MNPAg. O-Carboxymethylchitosan loaded silver nanoparticles were found to be more toxic, with a LC50 of 902.1 mg/L for γ-Fe2O3/Ag without reducing agent. Accumulation of silver on Artemia salina depends on the type of nanoparticle. Accumulation of nanoparticle containing polymers (carboxymethylchitosan/γ-Fe2O3/Ag without reducing agent, carboxymethylchitosan/γ-Fe2O3/Ag reduced with sucrose and carboxymethylchitosan/γ-Fe2O3/Ag reduced with NaBH4) were found to be higher than γ-Fe2O3/Ag reduced with NaBH4, γ-Fe2O3/Ag reduced with sucrose and γ-Fe2O3/Ag without reducing agent under the same experimental conditions. The antioxidant enzyme (CAT, SOD and GST) activities increased slightly following exposure, indicating that the toxic effects are related to oxidative stress. The combined results so far indicate that MNPA does not have the potential to affect aquatic organisms when released into the ecosystem.



中文翻译:

磁性O-羧甲基壳聚糖负载的银纳米颗粒对卤虫盐沼的响应的纳米生态毒理研究。

磁性银纳米颗粒(MNPAg)是具有无边界环境科学的有趣纳米技术材料,可用于消毒被致病细菌污染的水。使用MNPAg会导致环境(尤其是天然水源)中纳米材料污染的风险增加,并对生态系统产生有害影响。这项研究调查磁性O-羧甲基壳聚糖载银纳米颗粒在卤虫上的存活和酶活性。结果表明,死亡率随MNPAg浓度的增加而增加。O型羧甲基加载发现银纳米颗粒更有毒的,与LC 50的902.1毫克/升了γ-Fe 2 ö 3/ Ag,无还原剂。银在卤虫盐沼上的积累取决于纳米颗粒的类型。含纳米粒子的聚合物的积累(羧甲基/γ-的Fe 2 ö 3 /银无还原剂,羧甲基壳聚糖/γ-的Fe 2 ö 3 /银与蔗糖和羧甲基/γ-铁减少2 ö 3 /银减少用NaBH 4)为发现高于γ-的Fe 2 ö 3 /银用NaBH降低4,γ-的Fe 2 ö 3 /银与蔗糖和γ -铁还原2 ö 3/ Ag在相同的实验条件下不使用还原剂。暴露后,抗氧化酶(CAT,SOD和GST)的活性略有增加,表明毒性作用与氧化应激有关。迄今为止的综合结果表明,MNPA在释放到生态系统中时没有影响水生生物的潜力。

更新日期:2019-11-16
down
wechat
bug