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Interleukin-17 Inhibition in Spondyloarthritis Is Associated With Subclinical Gut Microbiome Perturbations and a Distinctive Interleukin-25-Driven Intestinal Inflammation.
Arthritis & Rheumatology ( IF 11.4 ) Pub Date : 2020-03-12 , DOI: 10.1002/art.41169 Julia Manasson 1 , David S Wallach 2 , Giuliana Guggino 3 , Matthew Stapylton 2 , Michelle H Badri 4 , Gary Solomon 1 , Soumya M Reddy 1 , Roxana Coras 5 , Alexander A Aksenov 6 , Drew R Jones 1 , Parvathy V Girija 1 , Andrea L Neimann 1 , Adriana Heguy 1 , Leopoldo N Segal 1 , Pieter C Dorrestein 6 , Richard Bonneau 7 , Monica Guma 5 , Francesco Ciccia 8 , Carles Ubeda 9 , Jose C Clemente 2 , Jose U Scher 1
Arthritis & Rheumatology ( IF 11.4 ) Pub Date : 2020-03-12 , DOI: 10.1002/art.41169 Julia Manasson 1 , David S Wallach 2 , Giuliana Guggino 3 , Matthew Stapylton 2 , Michelle H Badri 4 , Gary Solomon 1 , Soumya M Reddy 1 , Roxana Coras 5 , Alexander A Aksenov 6 , Drew R Jones 1 , Parvathy V Girija 1 , Andrea L Neimann 1 , Adriana Heguy 1 , Leopoldo N Segal 1 , Pieter C Dorrestein 6 , Richard Bonneau 7 , Monica Guma 5 , Francesco Ciccia 8 , Carles Ubeda 9 , Jose C Clemente 2 , Jose U Scher 1
Affiliation
To characterize the ecological effects of biologic therapies on the gut bacterial and fungal microbiome in psoriatic arthritis (PsA)/spondyloarthritis (SpA) patients.
中文翻译：
脊柱关节炎中的白细胞介素 17 抑制与亚临床肠道微生物组扰动和独特的白细胞介素 25 驱动的肠道炎症有关。
旨在描述生物疗法对银屑病关节炎 (PsA)/脊柱关节炎 (SpA) 患者肠道细菌和真菌微生物群的生态影响。
更新日期：2020-04-22
中文翻译：
脊柱关节炎中的白细胞介素 17 抑制与亚临床肠道微生物组扰动和独特的白细胞介素 25 驱动的肠道炎症有关。
旨在描述生物疗法对银屑病关节炎 (PsA)/脊柱关节炎 (SpA) 患者肠道细菌和真菌微生物群的生态影响。
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