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An extracellular microRNA can rescue lives in sepsis.
EMBO Reports ( IF 7.7 ) Pub Date : 2019-11-14 , DOI: 10.15252/embr.201949193
Kelly Van Looveren 1, 2 , Lise Van Wyngene 1, 2 , Claude Libert 1, 2
Affiliation  

Sepsis, or blood poisoning, is a savage response of the body to infection. It can lead to organ failure, blood pressure decline, heart failure, and coma. Between 20 and 30 million people suffer from sepsis each year, leading to 8 million deaths. Although certain people are more at risk than others (young children, elderly), anyone can develop sepsis. Patients are resuscitated and treated with antibiotics, and their organ functions are supported. Despite the investment in sepsis research during the previous decades, successful clinical trials are scarce and sepsis remains one of the most difficult and deadly unmet medical needs of today. A study in this issue now provides new insight into sepsis and points to a therapeutic future [1 ].

中文翻译:

细胞外的microRNA可以挽救败血症的生命。

败血症或血液中毒是身体对感染的野蛮反应。它可能导致器官衰竭,血压下降,心力衰竭和昏迷。每年有20至3000万人患有败血症,导致800万人死亡。尽管某些人比其他人(年幼的孩子,老人)的危险更大,但是任何人都可以患败血症。对患者进行复苏并用抗生素治疗,并支持其器官功能。尽管在过去的几十年中对脓毒症研究进行了投资,但是成功的临床试验仍然很少,脓毒症仍然是当今最困难和致命的未满足的医疗需求之一。对此问题的研究现在提供了对败血症的新见解,并指出了治疗的未来[1]。
更新日期:2020-01-07
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