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Kupffer Cells Mediate Systemic Antifungal Immunity.
Trends in Immunology ( IF 13.1 ) Pub Date : 2019-11-14 , DOI: 10.1016/j.it.2019.11.001
Carolina Coelho 1 , Rebecca A Drummond 2
Affiliation  

Patients with liver dysfunction have increased susceptibility to fungal infections. A recently published article (Sun et al.) describes the potential mechanism underlying this association, which maps to the antifungal activity of liver-resident Kupffer cells. This research highlights the importance of understanding tissue-specific immune responses in disease pathogenesis.

中文翻译:

枯否细胞介导全身抗真菌免疫力。

肝功能不全的患者对真菌感染的敏感性增加。最近发表的一篇文章(Sun等人)描述了这种关联的潜在机制,该机制对应于驻留于肝脏的库普弗细胞的抗真菌活性。这项研究突出了了解疾病发病机理中组织特异性免疫反应的重要性。
更新日期:2019-11-14
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