Association Between Toll‐Like Receptor 4 ( TLR4 ) and Triggering Receptor Expressed on Myeloid Cells 2 ( TREM2 ) Genetic Variants and Clinical Progression of Huntington's Disease,Movement Disorders

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Association Between Toll‐Like Receptor 4 ( TLR4 ) and Triggering Receptor Expressed on Myeloid Cells 2 ( TREM2 ) Genetic Variants and Clinical Progression of Huntington's Disease
Movement Disorders ( IF 7.4 ) Pub Date : 2019-11-14 , DOI: 10.1002/mds.27911
Romina Vuono _{1,

2} , Antonina Kouli ₁ , Emilie M Legault ₃ , Lauriane Chagnon ₃ , Kieren S Allinson ₄ , Alberto La Spada ₅ , , Ida Biunno ₆ , Roger A Barker ₁ , Janelle Drouin-Ouellet ₃

Affiliation

Although Huntington's disease (HD) is caused by a single dominant gene, it is clear that there are genetic modifiers that may influence the age of onset and disease progression.

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