Tissue Engineering emerged as a research field to solve problems derived from the loss of tissue and organ failure, specifically through the development of scaffolds. In this work, scaffolds were manufactured using collagen and chitosan as raw materials, evaluating the potential use of the latter as a substitute for collagen. Throughout this work, different proportions of these raw materials were used, and the influence of genipin (crosslinking agent) was evaluated, studying the variations in the mechanical and morphological properties of the scaffolds. The results obtained show that the properties of the scaffolds were strongly dependent on the biopolymer concentration used and on the concentrations of crosslinking agent. According to the results, the best mechanical properties were obtained for hybrid systems with high biopolymer concentrations (2 wt%), especially chitosan. Furthermore, the addition of a small amount of crosslinking agent (genipin) improved low biopolymer concentration systems (1 wt%), showing an improvement in the critical strain.

组织工程学已经成为一个研究领域，旨在解决因组织丧失和器官衰竭而引起的问题，特别是通过开发支架来解决。在这项工作中，使用胶原蛋白和壳聚糖作为原料制造了脚手架，评估了后者作为胶原蛋白替代品的潜在用途。在整个工作过程中，使用了不同比例的这些原料，并评估了京尼平（交联剂）的影响，研究了支架的力学和形态特性的变化。获得的结果表明，支架的性质很大程度上取决于所用生物聚合物的浓度和交联剂的浓度。根据结果​​，对于具有高生物聚合物浓度（2 wt％）的混合系统，尤其是壳聚糖，可以获得最佳的机械性能。此外，添加少量的交联剂（genipin）改善了低生物聚合物浓度系统（1 wt％），显示出临界应变的改善。