In The Lancet HIV, Alison Grant and colleagues report on the TB Fast Track cluster-randomised trial done in 24 South African primary health-care clinics. This pragmatic trial was designed to assess a nurse-led algorithm to stratify patients with advanced HIV disease (CD4 count <150 cells per μL) who were being evaluated for antiretroviral therapy (ART) to receive empirical tuberculosis treatment. The assessment was based on tuberculosis symptoms, body-mass index, point-of-care haemoglobin concentrations, and urine tuberculosis lipoarabinomannan assays. The algorithm was used to stratify patients into three categories on the basis of probability of tuberculosis (high, medium, and low).

中文翻译：

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晚期艾滋病毒的经验性结核病治疗。


在《柳叶刀 HIV》中，Alison Grant 及其同事报告了在 24 个南非初级卫生保健诊所进行的结核病快速通道整群随机试验。这项务实的试验旨在评估护士主导的算法，对正在接受抗逆转录病毒治疗 (ART) 评估以接受经验性结核病治疗的晚期 HIV 疾病患者（CD4 计数 <150 细胞/μL）进行分层。该评估基于结核病症状、体重指数、护理点血红蛋白浓度和尿液结核病阿拉伯糖甘露聚糖测定。该算法用于根据结核病概率将患者分为三类（高、中、低）。