Parylene (poly-p-xylylene), and its family of halogenated variants, have a long history for application as protective coatings and dielectric barriers. Among them, Parylene-C is the most popular due to its high impermeability to moisture, resistance to corrosive environments, and its vapor deposition polymerization, which is self-initiated and unterminated creating an extremely pure polymer coating. In order to apply these advantageous material characteristics in an environment containing ionizing radiation the effects of irradiation on the chemical stability of the polymer throughout the lifetime of the material needs to be further understood.

In this work, Fourier-transform infrared (FTIR) and two-dimensional correlation (2D-COS) spectroscopies were used to monitor the structural changes in a ~25 μm freestanding film of Parylene-C after subjection to X-ray irradiation. Samples were exposed to X-ray doses up to 100,000 Gy in atmospheric conditions, and IR spectra were measured after each 500Gy dose. Using 2D-COS it was possible to gain insight into the chemical stability and temporal mechanisms of the chemical reactions accompanying X-ray radiation of Parylene-C. Oxidation was observed by the production of a new species absorbing in the IR at 1697 and 1740 cm⁻¹. Additionally, skeletal stretching of the aliphatic back bone were positively correlated to C–O oxidation products found in the region of 1425–1100 cm⁻¹. The present work is confirmation that Parylene-C does experience chemical degradation from x-ray dose caused by oxidation of the polymer structure.

聚对二甲苯（聚对亚二甲苯基）及其卤代变体家族在用作保护性涂料和介电阻挡层方面具有悠久的历史。其中，Parylene-C因其对湿气的高度不渗透性，耐腐蚀性环境以及其自身引发且未终止的气相沉积聚合反应而被广泛使用，从而形成了极其纯净的聚合物涂层，因此是最受欢迎的。为了在包含电离辐射的环境中应用这些有利的材料特性，需要进一步了解辐射在整个材料寿命期间对聚合物化学稳定性的影响。

在这项工作中，傅立叶变换红外（FTIR）和二维相关（2D-COS）光谱学被用来监测X射线照射后〜25μm的Parylene-C独立式膜的结构变化。样品在大气条件下暴露于高达100,000 Gy的X射线剂量，并且在每次500 Gy剂量后测量IR光谱。使用2D-COS可以深入了解伴随Parylene-C的X射线辐射的化学反应的化学稳定性和时间机制。通过产生在1697和1740 cm ^-1处在IR中吸收的新物质，观察到氧化。此外，脂肪族背骨的骨骼伸展与在1425–1100 cm ^-1范围内发现的C–O氧化产物呈正相关。。目前的工作证实，Parylene-C确实会由于聚合物结构的氧化而从x射线剂量发生化学降解。