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An Inexpensive, simple calibration method for MALDI TOF/TOF systems.
Journal of Mass Spectrometry ( IF 1.9 ) Pub Date : 2019-11-27 , DOI: 10.1002/jms.4467
Matthew B O'Rourke 1, 2 , Matthew P Padula 2
Affiliation  

The array of analytes that can be measured by MADLI MS has created an equally vast range of calibration mixtures. The inherent problem with this is that acquiring all of them at commercial rates can be prohibitively expensive. With this in mind, we have created a low-cost alternative to the most commonly used peptide calibrants. We were able to achieve an overall 78 ppm mass accuracy across a mass range of 900 to 2500 Da which was comparable to the mass accuracy achievable with commercial peptide mixes and hence has become a viable alternative.

中文翻译:

一种廉价,简单的MALDI TOF / TOF系统校准方法。

可以通过MADLI MS测量的分析物阵列已经创建了同样广泛的校准混合物。固有的问题是,以商业价格购买所有这些工具可能会非常昂贵。考虑到这一点,我们为最常用的肽校正剂创造了一种低成本的替代品。我们能够在900到2500 Da的质量范围内达到78 ppm的整体质量精度,这与商业肽混合物可获得的质量精度相当,因此已成为可行的替代方法。
更新日期:2020-01-08
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