Three new cycloartane terpenoids, neriifolins A–C (1-3), together with one known compound, 24-methylenecycloartane (4), were isolated from the EtOAc extract of the leaves of Euphorbia neriifolia Linn (Euphorbiaceae). The structures of the new compounds were elucidated based on extensive spectroscopic analyses, particularly 1D and 2D NMR, and HR-ESI-MS. Compounds 1-3 showed cytotoxicity against breast cancer cells MCF-7 with IC₅₀ values of 13.14, 7.12 and 9.50 μM, respectively.

中文翻译：

---

大戟叶中的环烷三萜

三个新的环阿屯烷萜类化合物，neriifolins A-C（1 - 3），连同一种已知的化合物，24 methylenecycloartane（4）中，从叶的EtOAc萃取物中分离大戟花树林恩（大戟科）。根据广泛的光谱分析，特别是1D和2D NMR，以及HR-ESI-MS，阐明了新化合物的结构。化合物1 - 3对乳腺癌细胞MCF-7与IC显示细胞毒性₅₀的13.14，分别7.12和9.50μM，值。