OBJECTIVE To determine costs of hospitalization associated with bronchopulmonary dysplasia (BPD) during the first year in very low birth weight infants. STUDY DESIGN Retrospective cohort study of California births from 2008 to 2011 linking birth certificate, discharge records, and clinical data from California Perinatal Quality Care Collaborative. Inclusion: birth weight 401-1500 g, gestational age < 30 weeks, inborn or transferred within 2 days, alive at 36 weeks corrected, and without major congenital anomalies. Outcomes included cost and length of stay of initial hospitalization and rehospitalizations. RESULT Out of 7998 eligible infants, 2696 (33.7%) developed BPD. Median hospitalization cost in the first year was $377,871 per infant with BPD compared with $175,836 per infant without BPD (adjusted cost ratio 1.54, 95% confidence interval (CI) 1.49-1.59). Infants with BPD also had longer length of stay and a higher likelihood of rehospitalization. CONCLUSION BPD is associated with substantial resource utilization. Prevention strategies could help conserve healthcare resources.

中文翻译：

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生命第一年与支气管肺发育不良相关的住院费用。

目的确定极低体重婴儿第一年与支气管肺发育不良（BPD）相关的住院费用。研究设计将加利福尼亚州围产期质量保健协作组织的出生证明，出院记录和临床数据联系起来，对2008年至2011年加利福尼亚州的婴儿进行回顾性队列研究。纳入：出生体重401-1500 g，胎龄<30周，在2天之内出生或转移，在36周时还活着，并且没有重大的先天性异常。结果包括首次住院和再次住院的费用和住院时间。结果在7998名符合条件的婴儿中，有2696名（33.7％）发生了BPD。第一年的住院中位数费用为每名BPD婴儿377,871美元，而每名无BPD的婴儿为175,836美元（调整后费用比1.54，95％置信区间（CI）1.49-1.59）。BPD婴儿的住院时间也更长，再次住院的可能性也更高。结论BPD与大量资源利用相关。预防策略可以帮助节省医疗资源。