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Taking the polyQ load off.
Nature Reviews Molecular Cell Biology ( IF 81.3 ) Pub Date : 2019-12-01 , DOI: 10.1038/s41580-019-0193-4
Kim Baumann 1
Affiliation  

Compounds that tether toxic proteins with polyglutamine expansions to autophagosomes promote their autophagic clearance and might, in principle, be suitable for the treatment of associated neurodegenerative diseases.

中文翻译:

减轻polyQ的负担。

将具有聚谷氨酰胺扩展功能的毒性蛋白束缚到自噬体的化合物可促进其自噬清除,原则上可能适合于治疗相关的神经退行性疾病。
更新日期:2019-11-07
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