Curiosity plays a fundamental role for learning and memory, but the neural mechanisms that stimulate curiosity and its effect on memory are poorly understood. Accumulating evidence suggests that curiosity states are related to modulations in activity in the dopaminergic circuit and that these modulations impact memory encoding and consolidation for both targets of curiosity and incidental information encountered during curiosity states. To account for this evidence, we propose the Prediction, Appraisal, Curiosity, and Exploration (PACE) framework, which attempts to explain curiosity and memory in terms of cognitive processes, neural circuits, behavior, and subjective experience. The PACE framework generates testable predictions that can stimulate future investigation of the mechanisms underlying curiosity-related memory enhancements.

中文翻译：

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好奇心如何增强依赖海马体的记忆：预测、评估、好奇心和探索 (PACE) 框架

好奇心对学习和记忆起着重要作用，但人们对激发好奇心的神经机制及其对记忆的影响知之甚少。越来越多的证据表明，好奇心状态与多巴胺能回路中的活动调制有关，并且这些调制会影响好奇心状态期间遇到的好奇心目标和偶然信息的记忆编码和巩固。为了解释这一证据，我们提出了预测、评估、好奇心和探索 (PACE) 框架，该框架试图从认知过程、神经回路、行为和主观体验方面解释好奇心和记忆。PACE 框架生成可测试的预测，可以刺激未来对与好奇心相关的记忆增强机制的研究。