In recent years, health professionals and laypersons have disseminated misinformation regarding the consumption of coconut oil. Those encouraging the supplementation of coconut oil argue that it provides health benefits and protective cardiovascular effects. Our article examines the effects of coconut oil intake on the cardiometabolic profile by exploring various lipid indices, as well as potential non-lipid effects, such as weight loss. The majority of randomized controlled trials show that coconut oil intake or its supplementation increases low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDLC), and total cholesterol when compared with other vegetable oils. Lauric acid, a medium-chain fatty acid and the main constituent of coconut oil, increases LDL-C and HDL-C concentrations, since it plays a main role as a substrate for apolipoprotein (apo)A1 and apoB synthesis, which are the key molecules in HDL-C and LDL-C particles, respectively.Despite some findings demonstrating an increase in HDL-C, definitive long-term clinical trials are imperative to ascertain whether this effect is clinically relevant. In addition, coconut oil intake has failed as a weight loss strategy and should not be considered as a supplementation strategy to increase satiety and/or thermogenesis.If one desires to include coconut oil in the diet, then we suggest that it should be limited and encompassed within the current recommendations of SFA intake, which are up to 10% of total caloric intake.

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椰子油的摄入及其对心脏代谢的影响-一篇结构化文献综述。

近年来，卫生专业人员和外行散布了有关食用椰子油的错误信息。那些鼓励补充椰子油的人认为，椰子油具有健康益处和心血管保护作用。我们的文章通过探索各种脂质指数以及潜在的非脂质效应（例如体重减轻）来研究椰子油摄入量对心脏代谢的影响。大多数随机对照试验表明，与其他植物油相比，椰子油的摄入或补充椰子油会增加低密度脂蛋白胆固醇（LDL-C），高密度脂蛋白胆固醇（HDLC）和总胆固醇。月桂酸是一种中链脂肪酸，是椰子油的主要成分，可提高LDL-C和HDL-C的浓度，因为它在载脂蛋白（apo）A1和apoB的合成中起着主要作用，而载脂蛋白（apo）A1和apoB分别是HDL-C和LDL-C颗粒中的关键分子。必须进行长期临床试验以确定这种作用是否与临床相关。此外，椰子油的摄入已不能作为减肥策略，不应被视为增加饱腹感和/或生热的补充策略。包含在当前SFA摄入量建议中，最高占总热量摄入量的10％。尽管有一些发现表明HDL-C升高，但是确定性长期临床试验对于确定这种作用是否在临床上是必不可少的。此外，椰子油的摄入已不能作为减肥策略，不应被视为增加饱腹感和/或生热的补充策略。包含在当前SFA摄入量建议中，最高占总热量摄入量的10％。尽管有一些发现表明HDL-C升高，但是确定性的长期临床试验对于确定这种作用是否在临床上是必不可少的。此外，椰子油的摄入已不能作为减肥策略，不应被视为增加饱腹感和/或生热的补充策略。包含在当前SFA摄入量建议中，最高占总热量摄入量的10％。