当前位置：
X-MOL 学术
›
Arthritis Rheumatol.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
GRK5 Inhibition Attenuates Cartilage Degradation via Decreased NF-κB Signaling.
Arthritis & Rheumatology ( IF 11.4 ) Pub Date : 2020-03-05 , DOI: 10.1002/art.41152 Takuya Sueishi 1 , Yukio Akasaki 1 , Norio Goto 1 , Ichiro Kurakazu 1 , Masakazu Toya 1 , Masanari Kuwahara 1 , Taisuke Uchida 1 , Mitsumasa Hayashida 1 , Hidetoshi Tsushima 1 , Hirofumi Bekki 2 , Martin K Lotz 3 , Yasuharu Nakashima 1
Arthritis & Rheumatology ( IF 11.4 ) Pub Date : 2020-03-05 , DOI: 10.1002/art.41152 Takuya Sueishi 1 , Yukio Akasaki 1 , Norio Goto 1 , Ichiro Kurakazu 1 , Masakazu Toya 1 , Masanari Kuwahara 1 , Taisuke Uchida 1 , Mitsumasa Hayashida 1 , Hidetoshi Tsushima 1 , Hirofumi Bekki 2 , Martin K Lotz 3 , Yasuharu Nakashima 1
Affiliation
NF‐κB–dependent signaling is an important modulator in osteoarthritis (OA), and G protein–coupled receptor kinase 5 (GRK5) regulates the NF‐κB pathway. This study was undertaken to investigate the functional involvement of GRK5 in OA pathogenesis.
中文翻译：
GRK5抑制通过减少NF-κB信号传导减弱软骨降解。
依赖于NF-κB的信号传导是骨关节炎（OA）的重要调节剂，G蛋白偶联受体激酶5（GRK5）调节NF-κB途径。进行这项研究以研究GRK5在OA发病机理中的功能参与。
更新日期：2020-04-22
中文翻译：
GRK5抑制通过减少NF-κB信号传导减弱软骨降解。
依赖于NF-κB的信号传导是骨关节炎（OA）的重要调节剂，G蛋白偶联受体激酶5（GRK5）调节NF-κB途径。进行这项研究以研究GRK5在OA发病机理中的功能参与。
京公网安备 11010802027423号