Mid-life and late-life vascular risk factor burden and neuropathology in old age.,Annals of Clinical and Translational Neurology

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Mid-life and late-life vascular risk factor burden and neuropathology in old age.
Annals of Clinical and Translational Neurology ( IF 4.4 ) Pub Date : 2019-11-05 , DOI: 10.1002/acn3.50936
Sarah C Conner _{1,

2} , Matthew P Pase _{1,

3,

4,

5} , Herman Carneiro _{1,

6} , Mekala R Raman ₇ , Ann C McKee _{7,

8,

9,

10,

11} , Victor E Alvarez _{8,

9,

10,

11} , Jamie M Walker ₁₂ , Claudia L Satizabal _{1,

7,

12} , Jayandra J Himali _{1,

2,

7,

12} , Thor D Stein _{8,

9,

10,

11} , Alexa Beiser _{1,

2,

7} , Sudha Seshadri _{1,

7,

12}

Affiliation

Framingham Heart Study, Framingham, Massachusetts.
Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
Melbourne Dementia Research Centre, The Florey Institute for Neuroscience and Mental Health, Melbourne, Australia.
Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, Australia.
Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Australia.
Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.
Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.
Boston University, Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts.
Department of Veterans Affairs Medical Center, Bedford, Massachusetts.
VA Boston Healthcare System, Boston, Massachusetts.
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts.
Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas.

To determine whether vascular risk factor burden in mid‐ or late‐life associates with postmortem vascular and neurodegenerative pathologies in a community‐based sample.

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