CCA (Chromium Copper Arsenate) treated wood, widely used in outdoor residential structures and playgrounds, poses considerable dangers of leaching of its components to the environment.

In this study, mouse kidney samples were used to evaluate the effects of CCA, chromium trioxide (CrO₃) and arsenic pentoxide (As₂O₅) on cell pathophysiology by flow cytometry. Samples were collected after 14, 24, 48 and 96 h of animal exposure. While Cr had no statistically significant cytostatic effects, As₂O₅ induced a S-phase delay in animals exposed for 24 h, and over time a G0/G1 phase blockage. The effects of CCA in S-phase were similar, but more severe than those of As₂O₅. Since environmental and public health hazards due to the long durability of CCA-treated wood products, these data confirm that CCA has profoundly toxic effects on cell cycle, distinct from the compounds themselves. These cytostatic effects support cell cycle dynamics as a valuable endpoint to assess the toxicity of remaining CCA-treated infrastructures, and the expected increased waste stream over the coming decades.

经过CCA（砷酸铬铜）处理的木材广泛用于室外住宅结构和游乐场，存在其成分浸出到环境中的相当大的危险。

在这项研究中，使用小鼠肾脏样品通过流式细胞术评估CCA，三氧化铬（CrO ₃）和五氧化_二砷（As ₂ O ₅）对细胞病理生理学的影响。在动物暴露14、24、48和96小时后收集样品。尽管Cr在统计学上没有明显的细胞抑制作用，但是As ₂ O ₅导致暴露24小时的动物出现S期延迟，随着时间的流逝，G0 / G1期被阻滞。CCA在S相中的作用相似，但比As ₂ O ₅更为严重。由于CCA处理过的木制品的长期耐久性会给环境和公共健康带来危害，因此这些数据证实，CCA对化合物的细胞周期具有深远的毒性作用，这与化合物本身不同。这些细胞抑制作用支持细胞周期动力学，作为评估剩余的经过CCA处理的基础设施的毒性的有价值的终点，以及在未来几十年中预期增加的废物流。