Many material systems and phenomena elude nano- and atomic-scale characterization through electron microscopy due to the impact of the high energy beam that is employed. Cryogenic microscopy methods pioneered in structural biology offer a way to overcome this limitation by enabling the formation of images with an extremely low dose of electrons using automated data acquisition and advanced detectors. These methods are just beginning to be applied to non-biological materials, and their utility is demonstrated in a pair of recent papers by Cui and colleagues.

中文翻译：

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冷镜技术解决了能源研究中的热点问题

由于所使用的高能束的影响，许多材料系统和现象都无法通过电子显微镜进行纳米级和原子级的表征。结构生物学开创的低温显微镜方法通过使用自动数据采集和先进的检测器以极低剂量的电子来形成图像，从而提供了一种克服这一局限性的方法。这些方法才刚刚开始应用于非生物材料，Cui和同事在最近的两篇论文中证明了它们的实用性。