Since Jehovah’s Witness (JW) patients diagnosed with leukaemia refuse blood transfusions, they are often denied intensive chemotherapy for fear they could not survive myeloablation without blood transfusion support. Treatment of JW patients with acute leukaemia is challenging and carries a higher morbidity and mortality; however, the refusal of blood products should not be an absolute contraindication to offer multiple treatment modalities including haematopoietic stem cell transplantation. In this review we discuss their optimal management and describe alternative modalities to blood transfusions to provide sufficient oxygenation and prevent bleeding.

中文翻译：

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成人耶和华见证人急性白血病的治疗。

由于被诊断出患有白血病的耶和华见证人（JW）患者拒绝输血，因此他们常常被拒绝接受强化化疗，因为他们担心如果没有输血支持他们将无法进行消融。JW急性白血病患者的治疗具有挑战性，并具有较高的发病率和死亡率。但是，拒绝提供血液制品不应绝对是提供包括造血干细胞移植在内的多种治疗方式的禁忌症。在这篇综述中，我们讨论了他们的最佳治疗方法，并描述了输血的替代方式，以提供足够的充氧和预防出血。