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Is running associated with a lower risk of all-cause, cardiovascular and cancer mortality, and is the more the better? A systematic review and meta-analysis.
British Journal of Sports Medicine ( IF 12.022 ) Pub Date : 2020-08-01 , DOI: 10.1136/bjsports-2018-100493
Zeljko Pedisic,Nipun Shrestha,Stephanie Kovalchik,Emmanuel Stamatakis,Nucharapon Liangruenrom,Jozo Grgic,Sylvia Titze,Stuart Jh Biddle,Adrian E Bauman,Pekka Oja

Objective To investigate the association of running participation and the dose of running with the risk of all-cause, cardiovascular and cancer mortality. Design Systematic review and meta-analysis. Data sources Journal articles, conference papers and doctoral theses indexed in Academic Search Ultimate, CINAHL, Health Source: Nursing/Academic Edition, MasterFILE Complete, Networked Digital Library of Theses and Dissertations, Open Access Theses and Dissertations, PsycINFO, PubMed/MEDLINE, Scopus, SPORTDiscus and Web of Science. Eligibility criteria for selecting studies Prospective cohort studies on the association between running or jogging participation and the risk of all-cause, cardiovascular and/or cancer mortality in a non-clinical population of adults were included. Results Fourteen studies from six prospective cohorts with a pooled sample of 232 149 participants were included. In total, 25 951 deaths were recorded during 5.5–35 year follow-ups. Our meta-analysis showed that running participation is associated with 27%, 30% and 23% lower risk of all-cause (pooled adjusted hazard ratio (HR)=0.73; 95% confidence interval (CI) 0.68 to 0.79), cardiovascular (HR=0.70; 95% CI 0.49 to 0.98) and cancer (HR=0.77; 95% CI 0.68 to 0.87) mortality, respectively, compared with no running. A meta-regression analysis showed no significant dose–response trends for weekly frequency, weekly duration, pace and the total volume of running. Conclusion Increased rates of participation in running, regardless of its dose, would probably lead to substantial improvements in population health and longevity. Any amount of running, even just once a week, is better than no running, but higher doses of running may not necessarily be associated with greater mortality benefits.

中文翻译:

跑步与全因,心血管疾病和癌症的死亡风险降低有关,并且越多越好吗?系统的审查和荟萃分析。

目的探讨跑步参与和跑步剂量与全因,心血管疾病和癌症死亡风险的关系。设计系统的审查和荟萃分析。数据源期刊论文,会议论文和博士学位论文被收录在Academic Search Ultimate,CINAHL,卫生中资料来源:护理/学术版,MasterFILE Complete,网络论文和学位论文数字图书馆,开放式访问论文和学位论文,PsycINFO,PubMed / MEDLINE,Scopus ,SPORTDiscus和Web of Science。选择研究的资格标准包括关于跑步或慢跑参与与非临床成人人群全因,心血管和/或癌症死亡风险之间关联的前瞻性队列研究。结果纳入了来自六个前瞻性队列的十四项研究,汇总了232149名参与者。在5.5-35年的随访中,总共记录了25951例死亡。我们的荟萃分析显示,跑步参与与所有原因的风险降低27%,30%和23%(合并调整的危险比(HR)= 0.73; 95%的置信区间(CI)0.68至0.79),心血管疾病(与没有跑步相比,HR死亡率为0.70; 95%CI为0.49至0.98)和癌症(HR = 0.77; 95%CI为0.68至0.87)。荟萃回归分析显示,每周频率,每周持续时间,步伐和总跑步量没有明显的剂量反应趋势。结论不论其剂量如何,增加跑步的参与率可能会导致人口健康和长寿的显着改善。任何数量的跑步,
更新日期:2020-07-17
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