Background

This Dutch travel Vaccination Study (DiVeST) aimed to study adherence or compliance to Dutch travel health guidelines in travelling families and to identify risk groups to provide better advice and protection for international travellers.

Methods

Between 2016 and 2018, family members who travelled to Eastern Europe or outside Europe during the preceding year were recruited via Dutch secondary schools. The vaccination status of the travellers was assessed using questionnaires and vaccination records and hepatitis A virus antibody concentrations in dried blood spot (DBS) eluates. Subgroups of travellers with lower adherence to guidelines were identified.

Results

Of the 246 travellers that participated in this study, 155 (63%) travelled to destinations for which the HAV vaccination was recommended. Of these 155 travellers, 56 (36%) said they visited a pre-travel clinic, and 64 of them (41%) showed a valid HAV vaccination in their vaccination records. Of the 145 travellers with available DBS eluates, anti-HAV antibodies were detected in 98 (68%) of them.

Conclusions

We found that adherence to travel health guidelines, in terms of HAV vaccination, was suboptimal. According to our results, specific attention should be paid to children, persons visiting friends and relatives and those who travel relatively short distances.

中文翻译：

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遵守甲型肝炎旅行健康指南：荷兰旅行家庭的横断面血清阳性率研究 - 荷兰旅行疫苗接种研究 (DiVeST)

背景

这项荷兰旅行疫苗接种研究 (DiVeST) 旨在研究旅行家庭遵守或遵守荷兰旅行健康指南的情况，并确定风险人群，以便为国际旅行者提供更好的建议和保护。

方法

2016 年至 2018 年期间，前一年前往东欧或欧洲以外地区旅行的家庭成员是通过荷兰中学招募的。使用调查问卷和疫苗接种记录以及干血斑 (DBS) 洗脱液中的甲型肝炎病毒抗体浓度评估旅行者的疫苗接种状况。确定了对指南遵守程度较低的旅行者亚组。

结果

在参与这项研究的 246 名旅行者中，有 155 名 (63%) 前往推荐接种 HAV 疫苗的目的地。在这 155 名旅行者中，有 56 名（36%）表示他们去过旅行前诊所，其中 64 名（41%）在他们的疫苗接种记录中显示了有效的 HAV 疫苗接种。在有可用 DBS 洗脱液的 145 名旅行者中，有 98 名 (68%) 检测到了抗 HAV 抗体。

结论

我们发现，就 HAV 疫苗接种而言，遵守旅行健康指南并不理想。根据我们的结果，应特别注意儿童、探亲访友和短途旅行的人。