In our previous investigations, we demonstrated that certain living cells exposed to bio-electrosprays remained viable, and behaved as expected in comparison to control cells. These studies also extended to post-bio-electrosprayed cells being transplanted into mice, which demonstrated no rejection, and in fact they were seen to integrate with the surrounding host tissues. Therefore, highlighting bio-electrosprays as a front running bioplatform for engineering functional tissues for repair, replacement and rejuvenation of damaged and/ageing tissues. In the present studies, we take bio-electrosprays further into human health, investigating the possibility of this platform biotechnology to directly handle the smallest and most highly specialized cell in the human body, the spermatozoon. These studies demonstrated the ability for bio-electrosprays to directly handle human sperm without compromising their viability, while also demonstrating the technology’s capacity to encapsulate human sperm. These investigations reported herein present interesting implications to human reproductive science and medicine, while also having promising applicability to areas such as the agriculture and aquaculture industries.

中文翻译：

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生物电喷雾人类精子仍然可行

在我们之前的研究中，我们证明暴露于生物电喷雾的某些活细胞仍然可以存活，并且与对照细胞相比表现出预期的效果。这些研究还扩展到将生物电喷雾后的细胞移植到小鼠体内，这表明没有排斥反应，事实上，它们被发现与周围的宿主组织整合。因此，强调生物电喷雾作为用于工程功能组织修复、替换和恢复受损和/老化组织的前沿生物平台。在目前的研究中，我们将生物电喷雾进一步应用于人类健康，研究该平台生物技术直接处理人体内最小和高度特化的细胞——精子的可能性。这些研究证明了生物电喷雾能够直接处理人类精子而不影响其生存能力，同时也证明了该技术封装人类精子的能力。此处报告的这些调查对人类生殖科学和医学具有重要意义，同时也对农业和水产养殖业等领域具有广阔的应用前景。