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Deciphering cellular heterogeneity of pancreatic tumours.
Nature Cell Biology ( IF 17.3 ) Pub Date : 2019-11-01 , DOI: 10.1038/s41556-019-0419-x
Xiphias Ge Zhu 1 , Kivanc Birsoy 1
Affiliation  

Pancreatic ductal adenocarcinoma displays high levels of cellular heterogeneity, which is associated with drug resistance and high metastatic rates. A new study shows that tetraspanin CD9 marks PDAC tumour-initiating cells and functions as a regulator of glutamine metabolism.

中文翻译:

破译胰腺肿瘤的细胞异质性。

胰腺导管腺癌显示出高水平的细胞异质性,这与耐药性和高转移率有关。一项新的研究表明,四跨膜蛋白 CD9 标志着 PDAC 肿瘤起始细胞,并作为谷氨酰胺代谢的调节剂发挥作用。
更新日期:2019-11-04
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