In a recent article, Bisogno et al. reported in a randomized trial that addition of metronomic maintenance therapy (MMT) with vinorelbine plus cyclophosphamide for children with rhabdomyosarcoma resulted in a significant increase in overall and event-free survival. Although the mechanism of action remains to be fully elucidated, this study paves the way for further evaluation of MMT as a potential therapeutic strategy in pediatric patients with high-risk disease.

中文翻译：

---

横纹肌肉瘤的节律维持疗法。

在最近的一篇文章中，Bisogno等人。在一项随机试验中报道，长春瑞滨加环磷酰胺配合儿童节律维持疗法（MMT）可以改善横纹肌肉瘤患儿的总体生存率和无事件生存率。尽管其作用机理尚待充分阐明，但本研究为进一步评估MMT作为高危疾病儿科患者的潜在治疗策略铺平了道路。