We describe generation of human induced pluripotent stem cell (hiPSC) lines of three unrelated idiopathic late onset Parkinson disease patients and two healthy controls above 60 years of age without neurological diseases nor Ashkenazi ancestry. Human iPSC were derived from peripheral blood-erythroblasts using integration free episomal plasmids carrying four reprogramming factors OCT4, SOX2, c-MYC, KLF4 and BCL-XL. The hiPSC lines were characterized according to established criteria.

中文翻译：

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从三个无关的特发性帕金森病患者和两个无关的健康对照个体中产生5个hiPSC系。

我们描述了三名不相关的特发性晚期帕金森病患者和两个年龄在60岁以上且无神经系统疾病或Ashkenazi血统的健康对照的人诱导的多能干细胞（hiPSC）系的产生。使用携带四个重编程因子OCT4，SOX2，c-MYC，KLF4和BCL-XL的无整合游离型质粒，从外周血成血红细胞中衍生人iPSC 。根据确定的标准对hiPSC品系进行了表征。