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Photo-physical aspects of BODIPY-coumarin conjugated sensor and detection of Al3+ in MCF-7 cell
Supramolecular Chemistry ( IF 3.3 ) Pub Date : 2019-09-12 , DOI: 10.1080/10610278.2019.1659267
Kumari Somlata Kashyap 1 , Sumit Kumar Hira 2 , Swapan Dey 1
Affiliation  

ABSTRACT BODIPY azine bearing chemosensor R1 has been synthesised for selective detection of Al3+with visual colour change from red-purple to purple and photo-physical studies were explained through Förster Resonance Energy Transfer (FRET) mechanism. Chemosensor showed good sensing capability with high binding constant and lower Limit of Detection (LOD) towards Al3+. Cell viability and fluorescence microscopic experiments illustrated about the cytocompatibily of the sensor in presence of Al3+ in living cells (MCF-7). Graphical abstract

中文翻译:

BODIPY-香豆素共轭传感器的光物理特性和 MCF-7 细胞中 Al3+ 的检测

已合成带有 BODIPY azine 的化学传感器 R1,用于选择性检测 Al3+,视觉颜色从红紫色变为紫色,并通过 Förster 共振能量转移 (FRET) 机制解释光物理研究。化学传感器显示出良好的传感能力,对 Al3+ 具有高结合常数和较低的检测限 (LOD)。细胞活力和荧光显微实验说明了传感器在活细胞 (MCF-7) 中存在 Al3+ 时的细胞相容性。图形概要
更新日期:2019-09-12
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